NAD+ Research Compound | 99% Purity | Third Party Tested

Premium quality NAD+ research compound with verified 99% purity, complete documentation, and fast USA shipping. Buy NAD+ nicotinamide adenine dinucleotide from a trusted laboratory supplier.

Why Researchers Choose Our NAD+

Our NAD+ research compound represents the gold standard for cellular energy, sirtuins, and aging research requiring exceptional purity and documentation. Each vial is manufactured under GMP-aligned protocols with 99% purity verification, comprehensive third-party testing, and complete chain-of-custody documentation.

Key Trust Factors:

• Third-party tested and verified by independent laboratories
• USA manufactured under GMP-aligned procedures
• 99% purity with HPLC and MS verification
• Lot-matched COA included with every order
• Fast shipping with proper cold-chain handling
• Research-grade quality trusted by laboratories nationwide

---

What is NAD+? Complete Research Overview

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme present in all living cells that plays essential roles in cellular energy metabolism, DNA repair, and gene expression regulation. This research compound serves as a crucial cofactor for over 400 enzymatic reactions and represents one of the most fundamental molecules in cellular biochemistry and aging research.

Chemical Properties:

• Molecular Formula: C21H27N7O14P2
• Molecular Weight: 663.43 g/mol
• IUPAC Name: Nicotinamide adenine dinucleotide
• CAS Number: 53-84-9
• Purity: 99% (HPLC verified)
• Stability: Light sensitive, requires proper storage

---

NAD+ Research Applications & Mechanisms

Primary Research Focus Areas:

1. Cellular Energy Research Applications
NAD+ research demonstrates critical roles in glycolysis, citric acid cycle, and electron transport chain function. Studies indicate NAD+ serves as an essential cofactor for cellular respiration, ATP production, and metabolic flux regulation in various research models and cellular systems.

2. Sirtuin Research Studies
Laboratory studies show NAD+ functions as a required cofactor for sirtuin deacetylase activity, influencing gene expression, protein function, and cellular stress responses through chromatin modifications and transcriptional regulation in experimental applications.

3. DNA Repair Research Applications
Research indicates NAD+ is essential for PARP (poly ADP-ribose polymerase) enzyme function in DNA damage recognition and repair processes, providing insights into genomic stability, cellular stress responses, and DNA repair mechanisms in research studies.

4. Aging Research Studies
Preclinical studies suggest NAD+ levels decline with age and supplementation may influence longevity pathways, cellular senescence, and age-related metabolic dysfunction, offering insights into aging mechanisms and interventional strategies in various research applications.

---

Clinical Research & Scientific Studies

Cellular Energy Research Studies

A comprehensive study published in Nature Reviews Molecular Cell Biology examined NAD+’s roles in cellular energy metabolism. Researchers found that NAD+ availability directly impacts mitochondrial function, ATP production, and cellular energy homeostasis across multiple tissue types.

Study Results:

• Essential cofactor for 400+ enzymatic reactions
• Critical for mitochondrial respiration efficiency
• Direct correlation with cellular ATP levels
• Required for metabolic pathway regulation

Sirtuin Research Findings

Research published in Cell demonstrated NAD+’s essential role in sirtuin enzyme function, showing direct requirement for sirtuin catalytic activity, regulation of chromatin structure and gene expression, influence on metabolic gene programs, and modulation of cellular stress responses in research models.

Aging Research Applications

Studies in Science explored NAD+’s relationship to aging processes, demonstrating age-related decline in NAD+ levels, restoration of youthful cellular function with supplementation, improved mitochondrial biogenesis, and enhanced DNA repair capacity in experimental subjects.

---

NAD+ vs NAD+ Precursors: Research Comparison

Property	NAD+	NMN/NR Precursors
Bioavailability	Limited oral	Enhanced
Cellular Uptake	Direct but complex	Indirect via conversion
Research Applications	Direct supplementation	Biosynthesis studies
Stability	pH dependent	More stable
Cost	Lower	Higher

---

Product Specifications That Matter

Quality Control Standards:

• Identity Verification: Confirmed via HPLC and Mass Spectrometry
• Purity Analysis: 99% by multiple analytical methods
• pH Testing: Optimal range maintained
• Water Content: <5% by Karl Fischer
• Form: Sterile lyophilized powder
• Packaging: Light-protected Type I borosilicate glass vials
• Storage: 2-8°C (short term), -20°C (long term)

---

Laboratory Usage & Reconstitution Protocol

Reconstitution Guidelines:

1. Solvent Selection: Use sterile phosphate buffer or appropriate medium
2. pH Maintenance: Ensure neutral to slightly alkaline pH
3. Light Protection: Prepare and store in dark conditions
4. Storage: Reconstituted solution stable 7 days at 2-8°C
5. Handling: Use sterile technique throughout process

Recommended Laboratory Protocols:

• Cell Culture Studies: 0.1-5 mM concentration range
• Enzymatic Assays: Follow established protocols
• Storage Buffer: Phosphate buffer pH 7.4 recommended
• Aliquoting: Prepare working concentrations to minimize light exposure

---

Frequently Asked Questions (FAQ)

Q: What makes NAD+ different from NAD+ precursors like NMN?
A: NAD+ is the active coenzyme form that directly participates in enzymatic reactions, while precursors like NMN must be converted to NAD+ intracellularly, offering different research applications and bioavailability profiles.

Q: How pure is your NAD+?
A: Our NAD+ exceeds 99% purity as verified by HPLC and mass spectrometry, with complete analytical documentation provided with each batch.

Q: Why is NAD+ light sensitive?
A: NAD+ contains nicotinamide moieties that are susceptible to photodegradation, requiring storage and handling in dark conditions to maintain stability and biological activity.

Q: How should NAD+ be stored?
A: Lyophilized NAD+ should be stored in dark, dry conditions at 2-8°C for short term or -20°C for long term. Once reconstituted, use within 7 days when refrigerated and protected from light.

---

Research Disclaimer & Legal Notice

Important Research Use Only Statement:
This NAD+ research compound is supplied exclusively for in-vitro laboratory research and scientific investigation purposes. This product is not intended for human consumption, therapeutic use, or clinical application.

Legal Compliance:

• Not for human or veterinary use
• Research use only – not a dietary supplement
• Not FDA approved for therapeutic applications
• Must be 21+ years old to purchase

RUO disclaimer: For laboratory research use only. Not for human or veterinary consumption or therapeutic applications.