IGF-1 LR3 Research Peptide | 99% Purity | Third Party Tested

Premium quality IGF-1 LR3 research peptide with verified 99% purity, complete documentation, and fast USA shipping. Buy IGF-1 Long R3 from a trusted laboratory supplier.

Why Researchers Choose Our IGF-1 LR3

Our IGF-1 LR3 (Long Arginine 3-IGF-1) research peptide represents the gold standard for growth factor and anabolic research requiring exceptional purity and documentation. Each vial is manufactured under GMP-aligned protocols with 99% purity verification, comprehensive third-party testing, and complete chain-of-custody documentation.

Key Trust Factors:

• Third-party tested and verified by independent laboratories
• USA manufactured under GMP-aligned procedures
• 99% purity with HPLC and MS verification
• Lot-matched COA included with every order
• Fast shipping with proper cold-chain handling
• Research-grade quality trusted by laboratories nationwide

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What is IGF-1 LR3? Complete Research Overview

IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 (IGF-1) with enhanced stability and reduced binding affinity to IGF-binding proteins (IGFBPs). This research peptide features an extended N-terminal sequence and arginine substitution at position 3, resulting in improved bioavailability and prolonged activity for comprehensive growth factor research applications.

Chemical Properties:

• Molecular Formula: C400H625N111O115S9
• Molecular Weight: 9117.5 g/mol
• Structure: 83-amino acid polypeptide chain
• Half-life: 20-30 hours (vs 10-12 hours for IGF-1)
• Purity: 99% (HPLC verified)
• IGFBP Binding: Reduced compared to native IGF-1

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IGF-1 LR3 Research Applications & Mechanisms

Primary Research Focus Areas:

1. Cell Proliferation Research
IGF-1 LR3 research demonstrates significant effects on cellular division and growth through IGF-1 receptor activation. Studies indicate the compound stimulates DNA synthesis, protein production, and cellular metabolic activity in various research models and cell types.

2. Muscle Development Research Studies
Laboratory studies show IGF-1 LR3 influences myoblast differentiation, satellite cell activation, and muscle fiber hypertrophy through anabolic signaling pathways, providing insights into muscle growth and regeneration mechanisms in experimental applications.

3. Metabolic Research Applications
Research indicates IGF-1 LR3 affects glucose uptake, insulin sensitivity, and cellular energy metabolism through PI3K/Akt pathway modulation, offering valuable insights into metabolic regulation and glucose homeostasis in research studies.

4. Tissue Repair Research Studies
Preclinical studies suggest IGF-1 LR3 enhances wound healing, bone formation, and neural regeneration through growth factor signaling cascades, making it valuable for regenerative medicine research applications.

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Clinical Research & Scientific Studies

Cell Growth Research Studies

A landmark study published in Growth Hormone and IGF Research examined IGF-1 LR3’s effects on cellular proliferation in various cell lines. Researchers found that IGF-1 LR3 treatment significantly enhanced cell division rates and metabolic activity compared to native IGF-1.

Study Results:

• 250% increase in cell proliferation rates
• Enhanced DNA synthesis activity
• Improved protein synthesis markers
• Sustained growth factor signaling

Muscle Research Findings

Research published in Journal of Applied Physiology demonstrated IGF-1 LR3’s effects on muscle development, showing significant increase in myoblast differentiation, enhanced satellite cell proliferation, improved muscle fiber cross-sectional area, and accelerated muscle regeneration in experimental models.

Metabolic Research Applications

Studies in Endocrinology explored IGF-1 LR3’s metabolic effects, demonstrating enhanced glucose uptake in muscle cells, improved insulin sensitivity markers, increased glycogen synthesis, and optimized cellular energy metabolism in research subjects.

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IGF-1 LR3 vs Native IGF-1: Research Comparison

Property	IGF-1 LR3	Native IGF-1
Half-life	20-30 hours	10-12 hours
IGFBP Binding	Reduced	High
Bioavailability	Enhanced	Limited
Research Applications	Extended studies	Acute investigations
Stability	Improved	Labile

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Product Specifications That Matter

Quality Control Standards:

• Identity Verification: Confirmed via HPLC and Mass Spectrometry
• Purity Analysis: 99% by multiple analytical methods
• Endotoxin Testing: <10 EU/mg
• Water Content: <5% by Karl Fischer
• Form: Sterile lyophilized powder
• Packaging: Type I borosilicate glass vials
• Storage: 2-8°C (short term), -20°C (long term)

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Laboratory Usage & Reconstitution Protocol

Reconstitution Guidelines:

1. Solvent Selection: Use sterile bacteriostatic water or appropriate buffer
2. Concentration: Calculate based on experimental requirements
3. Mixing: Add solvent slowly to vial wall, swirl gently
4. Storage: Reconstituted solution stable 30 days at 2-8°C
5. Handling: Use sterile technique throughout process

Recommended Laboratory Protocols:

• Cell Culture Studies: 10-100 ng/mL concentration range
• Growth Factor Assays: Follow established protocols
• Storage Buffer: PBS with 0.1% BSA recommended
• Aliquoting: Prepare working concentrations to minimize freeze-thaw cycles

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Frequently Asked Questions (FAQ)

Q: What makes IGF-1 LR3 different from regular IGF-1?
A: IGF-1 LR3 has reduced binding to IGFBPs and extended half-life, providing more sustained growth factor signaling and improved bioavailability for research applications requiring prolonged activity.

Q: How pure is your IGF-1 LR3?
A: Our IGF-1 LR3 exceeds 99% purity as verified by HPLC and mass spectrometry, with complete analytical documentation provided with each batch.

Q: Can IGF-1 LR3 be studied with insulin or other growth factors?
A: Many researchers investigate IGF-1 LR3 in combination with insulin, growth hormone, and other anabolic factors to study synergistic effects on cellular growth and metabolic pathways.

Q: How should IGF-1 LR3 be stored?
A: Lyophilized IGF-1 LR3 remains stable at room temperature for weeks but should be stored at 2-8°C for optimal longevity. Once reconstituted, use within 30 days when refrigerated.

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Research Disclaimer & Legal Notice

Important Research Use Only Statement:
This IGF-1 LR3 research peptide is supplied exclusively for in-vitro laboratory research and scientific investigation purposes. This product is not intended for human consumption, therapeutic use, or clinical application.

Legal Compliance:

• Not for human or veterinary use
• Research use only – not a dietary supplement
• Not FDA approved for therapeutic applications
• Must be 21+ years old to purchase

RUO disclaimer: For laboratory research use only. Not for human or veterinary consumption or therapeutic applications.