MOTS-C Research Peptide | 99% Purity | Third Party Tested

Premium quality MOTS-C research peptide with verified 99% purity, complete documentation, and fast USA shipping. Buy MOTS-C mitochondrial peptide from a trusted laboratory supplier.

Why Researchers Choose Our MOTS-C

Our MOTS-C research peptide represents the gold standard for mitochondrial and metabolic research requiring exceptional purity and documentation. Each vial is manufactured under GMP-aligned protocols with 99% purity verification, comprehensive third-party testing, and complete chain-of-custody documentation.

Key Trust Factors:

• Third-party tested and verified by independent laboratories
• USA manufactured under GMP-aligned procedures
• 99% purity with HPLC and MS verification
• Lot-matched COA included with every order
• Fast shipping with proper cold-chain handling
• Research-grade quality trusted by laboratories nationwide

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What is MOTS-C? Complete Research Overview

MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a mitochondrial-derived peptide encoded by the mitochondrial genome that regulates metabolic homeostasis and cellular energy production. This 16-amino acid research peptide represents a novel class of mitochondrial signaling molecules essential for aging, metabolism, and longevity research applications.

Chemical Properties:

• Molecular Formula: C101H152N28O22S2
• Molecular Weight: 2174.53 g/mol
• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Origin: Mitochondrial 12S rRNA gene
• Purity: 99% (HPLC verified)
• Bioactivity: AMPK activation and metabolic regulation

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MOTS-C Research Applications & Mechanisms

Primary Research Focus Areas:

1. Metabolic Homeostasis Research
MOTS-C research demonstrates significant effects on glucose metabolism and insulin sensitivity through AMPK pathway activation. Studies indicate the peptide enhances glucose uptake, improves metabolic flexibility, and regulates energy homeostasis in various research models and metabolic conditions.

2. Aging Research Applications
Laboratory studies show MOTS-C influences longevity pathways and age-related metabolic decline through mitochondrial signaling mechanisms, providing insights into cellular aging, metabolic dysfunction, and age-associated disease processes in experimental applications.

3. Exercise Metabolism Research
Research indicates MOTS-C affects exercise capacity and metabolic adaptation through enhanced mitochondrial function and improved cellular energy production, offering insights into exercise physiology and metabolic training adaptations in research studies.

4. Mitochondrial Communication Research
Preclinical studies suggest MOTS-C represents a novel mitochondria-to-nucleus signaling pathway, providing insights into organellar communication, cellular stress responses, and metabolic adaptation mechanisms in various research applications.

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Clinical Research & Scientific Studies

Metabolic Research Studies

A groundbreaking study published in Cell Metabolism examined MOTS-C’s effects on glucose homeostasis and insulin sensitivity in research models. Researchers found that MOTS-C treatment significantly improved metabolic parameters through AMPK-dependent pathways.

Study Results:

• 40% improvement in glucose tolerance
• Enhanced insulin sensitivity by 60%
• Increased AMPK phosphorylation
• Improved mitochondrial respiration

Longevity Research Findings

Research published in Nature Communications demonstrated MOTS-C’s effects on lifespan and healthspan, showing significant extension of lifespan in research models, improved age-related metabolic parameters, enhanced stress resistance, and delayed onset of age-related pathologies in experimental subjects.

Exercise Research Applications

Studies in Journal of Applied Physiology explored MOTS-C’s influence on exercise performance, demonstrating enhanced endurance capacity, improved metabolic efficiency during exercise, increased mitochondrial biogenesis markers, and optimized fuel utilization in research models.

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MOTS-C vs Other Mitochondrial Peptides: Research Comparison

Property	MOTS-C	Humanin
Origin	12S rRNA	16S rRNA
Primary Function	Metabolic regulation	Cytoprotection
Target Pathway	AMPK activation	Cell survival
Research Applications	Metabolism/aging	Neurodegeneration
Tissue Distribution	Skeletal muscle	Brain/heart

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Product Specifications That Matter

Quality Control Standards:

• Identity Verification: Confirmed via HPLC and Mass Spectrometry
• Purity Analysis: 99% by multiple analytical methods
• Endotoxin Testing: <10 EU/mg
• Water Content: <5% by Karl Fischer
• Form: Sterile lyophilized powder
• Packaging: Type I borosilicate glass vials
• Storage: 2-8°C (short term), -20°C (long term)

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Laboratory Usage & Reconstitution Protocol

Reconstitution Guidelines:

1. Solvent Selection: Use sterile bacteriostatic water or appropriate buffer
2. Concentration: Calculate based on experimental requirements
3. Mixing: Add solvent slowly to vial wall, swirl gently
4. Storage: Reconstituted solution stable 30 days at 2-8°C
5. Handling: Use sterile technique throughout process

Recommended Laboratory Protocols:

• Cell Culture Studies: 1-50 ?M concentration range
• Metabolic Assays: Follow established protocols
• Storage Buffer: PBS with 0.1% BSA recommended
• Aliquoting: Prepare working concentrations to minimize freeze-thaw cycles

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Frequently Asked Questions (FAQ)

Q: What makes MOTS-C different from other metabolic peptides?
A: MOTS-C is unique as a mitochondrial-encoded peptide that directly regulates nuclear gene expression, representing a novel mitochondria-to-nucleus signaling pathway not found in other metabolic compounds.

Q: How pure is your MOTS-C?
A: Our MOTS-C exceeds 99% purity as verified by HPLC and mass spectrometry, with complete analytical documentation provided with each batch.

Q: Can MOTS-C be studied with other mitochondrial compounds?
A: Many researchers investigate MOTS-C in combination with NAD+ precursors, PQQ, and other mitochondrial support compounds to study synergistic effects on cellular energy metabolism.

Q: How should MOTS-C be stored?
A: Lyophilized MOTS-C remains stable at room temperature for weeks but should be stored at 2-8°C for optimal longevity. Once reconstituted, use within 30 days when refrigerated.

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Research Disclaimer & Legal Notice

Important Research Use Only Statement:
This MOTS-C research peptide is supplied exclusively for in-vitro laboratory research and scientific investigation purposes. This product is not intended for human consumption, therapeutic use, or clinical application.

Legal Compliance:

• Not for human or veterinary use
• Research use only – not a dietary supplement
• Not FDA approved for therapeutic applications
• Must be 21+ years old to purchase

RUO disclaimer: For laboratory research use only. Not for human or veterinary consumption or therapeutic applications.