Retatrutide

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Research Use Only

For Laboratory Research Only. Not for Human Consumption.

This product is intended solely for research purposes and complies with all applicable research chemical regulations.
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Price Price range: $137.75 through $741.00 Price range: $130.50 through $702.00 Price range: $123.25 through $663.00
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Retatrutide Research Peptide | 99% Purity | Third Party Tested

Premium quality Retatrutide research peptide with verified 99% purity, complete documentation, and fast USA shipping. Buy Retatrutide triple receptor agonist from a trusted laboratory supplier.

Why Researchers Choose Our Retatrutide

Our Retatrutide research peptide represents the gold standard for multi-receptor agonist and metabolic research requiring exceptional purity and documentation. Each vial is manufactured under GMP-aligned protocols with 99% purity verification, comprehensive third-party testing, and complete chain-of-custody documentation.

Key Trust Factors:

  • Third-party tested and verified by independent laboratories
  • USA manufactured under GMP-aligned procedures
  • 99% purity with HPLC and MS verification
  • Lot-matched COA included with every order
  • Fast shipping with proper cold-chain handling
  • Research-grade quality trusted by laboratories nationwide

What is Retatrutide? Complete Research Overview

Retatrutide is an investigational triple receptor agonist that simultaneously activates GLP-1, GIP, and glucagon receptors. This research peptide represents a novel approach to metabolic regulation, offering unprecedented insights into multi-pathway targeting for comprehensive metabolic research applications and obesity studies.

Chemical Properties:

  • Molecular Formula: C225H348N60O68S
  • Molecular Weight: 5312.15 g/mol
  • Structure: Modified peptide with fatty acid conjugation
  • Receptor Activity: GLP-1R, GIPR, GCGR triple agonist
  • Purity: 99% (HPLC verified)
  • Half-life: Extended through albumin binding

Retatrutide Research Applications & Mechanisms

Primary Research Focus Areas:

1. Multi-Receptor Pharmacology Research
Retatrutide research demonstrates simultaneous activation of three distinct metabolic receptors with balanced activity profiles. Studies indicate the compound provides unique insights into receptor crosstalk, pathway integration, and synergistic effects in metabolic regulation research models.

2. Weight Management Research Studies
Laboratory studies show Retatrutide influences body weight regulation through multiple complementary mechanisms including appetite suppression, enhanced satiety, improved glucose homeostasis, and increased energy expenditure in experimental applications.

3. Glucose Metabolism Research
Research indicates Retatrutide affects glucose homeostasis through insulin sensitization, glucagon regulation, and incretin pathway modulation, offering comprehensive insights into diabetes research and glycemic control mechanisms in research studies.

4. Energy Balance Research Applications
Preclinical studies suggest Retatrutide influences energy expenditure and thermogenesis through multiple receptor-mediated pathways, providing insights into metabolic rate regulation and energy balance mechanisms in various research applications.


Clinical Research & Scientific Studies

Multi-Receptor Research Studies

A breakthrough study published in Nature Medicine examined Retatrutide’s triple receptor activation profile in research models. Researchers found that balanced multi-receptor agonism produced superior metabolic outcomes compared to single-receptor approaches.

Study Results:

  • Balanced GLP-1R, GIPR, GCGR activation
  • Superior weight reduction vs single agonists
  • Improved glucose homeostasis markers
  • Enhanced satiety and appetite control

Weight Management Research Findings

Research published in The Lancet demonstrated Retatrutide’s effects on body weight regulation, showing significant weight reduction in research subjects, sustained appetite suppression, improved metabolic parameters, and dose-dependent efficacy across study populations.

Metabolic Research Applications

Studies in Diabetes Care explored Retatrutide’s metabolic effects, demonstrating improved insulin sensitivity, enhanced glucose tolerance, reduced inflammatory markers, and optimized lipid profiles in experimental subjects with metabolic dysfunction.


Retatrutide vs Dual Agonists: Research Comparison

Property Retatrutide (Triple) Tirzepatide (Dual)
Receptor Targets GLP-1R, GIPR, GCGR GLP-1R, GIPR
Glucagon Activity Present None
Weight Loss Efficacy Superior Excellent
Research Applications Comprehensive Dual pathway
Mechanistic Complexity Higher Moderate

Product Specifications That Matter

Quality Control Standards:

  • Identity Verification: Confirmed via HPLC and Mass Spectrometry
  • Purity Analysis: 99% by multiple analytical methods
  • Endotoxin Testing: <10 EU/mg
  • Water Content: <5% by Karl Fischer
  • Form: Sterile lyophilized powder
  • Packaging: Type I borosilicate glass vials
  • Storage: 2-8°C (short term), -20°C (long term)

Laboratory Usage & Reconstitution Protocol

Reconstitution Guidelines:

  1. Solvent Selection: Use sterile bacteriostatic water or appropriate buffer
  2. Concentration: Calculate based on experimental requirements
  3. Mixing: Add solvent slowly to vial wall, swirl gently
  4. Storage: Reconstituted solution stable 30 days at 2-8°C
  5. Handling: Use sterile technique throughout process

Recommended Laboratory Protocols:

  • Cell Culture Studies: 1-100 nM concentration range
  • Receptor Binding Assays: Follow established protocols
  • Storage Buffer: PBS with 0.1% BSA recommended
  • Aliquoting: Prepare working concentrations to minimize freeze-thaw cycles

Frequently Asked Questions (FAQ)

Q: What makes Retatrutide different from other GLP-1 analogs?
A: Retatrutide uniquely activates three receptors (GLP-1, GIP, and glucagon) simultaneously, providing comprehensive metabolic pathway targeting that single or dual agonists cannot achieve.

Q: How pure is your Retatrutide?
A: Our Retatrutide exceeds 99% purity as verified by HPLC and mass spectrometry, with complete analytical documentation provided with each batch.

Q: Can Retatrutide be studied with other metabolic compounds?
A: Many researchers investigate Retatrutide in combination with insulin sensitizers, SGLT2 inhibitors, and other metabolic agents to study additive or synergistic effects on glucose and weight regulation.

Q: How should Retatrutide be stored?
A: Lyophilized Retatrutide remains stable at room temperature for weeks but should be stored at 2-8°C for optimal longevity. Once reconstituted, use within 30 days when refrigerated.


Research Disclaimer & Legal Notice

Important Research Use Only Statement:
This Retatrutide research peptide is supplied exclusively for in-vitro laboratory research and scientific investigation purposes. This product is not intended for human consumption, therapeutic use, or clinical application.

Legal Compliance:

  • Not for human or veterinary use
  • Research use only – not a dietary supplement
  • Not FDA approved for therapeutic applications
  • Must be 21+ years old to purchase

RUO disclaimer: For laboratory research use only. Not for human or veterinary consumption or therapeutic applications.

Certificate of Analysis (COA)

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Retatrutide research peptide 5mg vial 99 purity lab tested (2)Retatrutide
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